![]() ![]() This pattern is observed in infection and inflammatory diseases, such as inflammatory bowel diseases. This is commonly seen with chronic kidney failure. This happens in diseases that affect the bone marrow, such as chemotherapy and Aplastic anemia, or Wiskott-Aldrich syndrome. Since older cells are smaller, this suggests a problem in the production line of the platelets, so the number of platelets may also be less. It may occur with different platelet counts similar to high MPV. Low MPV tells that the platelets are smaller than the ideal size.
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